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1

Cyclooxygenase-2 Inhibitors. Synthesis and Pharmacological Activities of 5-Methanesulfonamido-1-indanone Derivatives

Black, W. Cameron, Li, Chun-Sing, Chan, Chi-Chung, Ford-Hutchinson, Anthony W., Gauthier, Jacques-Yves, Gordon, Robert, Guay, Daniel, Kargman, Stacia, Lau, Cheuk K.

Journal:

Journal of Medicinal Chemistry

Year:

1995

Language:

english

File:

PDF, 1.20 MB

english, 1995

2

The Binding of Scandium Ions to Transferrin in vivo and in vitro

Anthony W. Ford-Hutchinson, Deryck J. Perkins

Journal:

Year:

1971

Language:

english

File:

PDF, 476 KB

english, 1971

3

Development of 2,3-dihydro-6-(3-phenoxypropyl)-2-(2-phenylethyl)-5-benzofuranol (L-670,630) as a potent and orally active inhibitor of 5-lipoxygenase

Lau, Cheuk K., Belanger, Patrice C., Dufresne, Claude, Scheigetz, John, Therien, Michel, Fitzsimmons, Brian, Young, Robert N., Ford-Hutchinson, Anthony W., Riendeau, Denis

Journal:

Journal of Medicinal Chemistry

Year:

1992

Language:

english

File:

PDF, 2.66 MB

english, 1992

4

Application of reversed phase high performance liquid chromatography to the analysis of sulphidopeptide leukotrienes in pig bile

Philip Tagari, Diane Ethier, Anthony Ford-Hutchinson, Maria Cirino

Journal:

Biomedical Chromatography

Year:

1990

Language:

english

File:

PDF, 397 KB

english, 1990

5

Leukotriene antagonists and inhibitors as modulators of IgE-mediated reactions

Anthony W. Ford-Hutchinson

Journal:

Seminars in Immunopathology

Year:

1993

Language:

english

File:

PDF, 964 KB

english, 1993

6

Assessment of thein vivobiochemical efficacy of orally active leukotriene biosynthesis inhibitors

Philip Tagari, Christine Brideau, Chi Chan, Richard Frenette, Cheryl Black, Anthony Ford-Hutchinson

Journal:

Inflammation Research

Year:

1993

Language:

english

File:

PDF, 852 KB

english, 1993

7

Effects of Synthetic Leukotrienes on Local Blood Flow and Vascular Permeability in Porcine Skin.

Chi-Chung Chan,, Ford-Hutchinson, Anthony

Journal:

The Journal of Investigative Dermatology

Year:

1985

File:

PDF, 1.59 MB

1985

8

Identification and isolation of a membrane protein necessary for leukotriene production

Miller, Douglas K., Gillard, John W., Vickers, Philip J., Sadowski, Sharon, Léveillé, Claire, Mancini, Joseph A., Charleson, Peter, Dixon, Richard A. F., Ford-Hutchinson, Anthony W., Fortin, Réjean

Journal:

Year:

1990

File:

PDF, 473 KB

1990

9

Elevated cysteinyl leukotriene excretion in experimental glomerulonephritis

Petric, Rosemary, Ford-Hutchinson, Anthony W

Journal:

Kidney International

Year:

1994

Language:

english

File:

PDF, 1015 KB

english, 1994

10

Characterization of the recombinant human prostanoid DP receptor and identification of L-644,698, a novel selective DP agonist

D. Hamish Wright, Kathleen M. Metters, Mark Abramovitz, Anthony W. Ford-Hutchinson

Journal:

British Journal of Pharmacology

Year:

1998

Language:

english

File:

PDF, 374 KB

english, 1998

11

The human prostanoid DP receptor stimulates mucin secretion in LS174T cells

D Hamish Wright, Anthony W Ford-Hutchinson, Kris Chadee, Kathleen M Metters

Journal:

British Journal of Pharmacology

Year:

2000

Language:

english

File:

PDF, 282 KB

english, 2000

12

Common structural features of mapeg—a widespread superfamily of membrane associated proteins with highly divergent functions in eicosanoid and glutathione metabolism

Per-Johan Jakobsson, Ralf Morgenstern, Joseph Mancini, Anthony Ford-Hutchinson, Bengt Persson

Journal:

Protein Science

Year:

1999

Language:

english

File:

PDF, 225 KB

english, 1999

13

Characterization of arachidonic-acid-metabolizing enzymes in adult Schistisoma mansoni

Heba Abdel Baset, Gary P. O'Neill, Anthony W. Ford-Hutchinson

Journal:

Molecular and Biochemical Parasitology

Year:

1995

Language:

english

File:

PDF, 1.26 MB

english, 1995

14

A novel biological role for prostaglandin D2 is suggested by distribution studies of the rat DP prostanoid receptor

D.Hamish Wright, Francois Nantel, Kathleen M Metters, Anthony W Ford-Hutchinson

Journal:

European Journal of Pharmacology

Year:

1999

Language:

english

File:

PDF, 2.94 MB

english, 1999

15

Chemical Modifications of the Tryptophan Groups of Transferrin

Anthony W. Ford-Hutchinson, Deryck J. Perkins

Journal:

Year:

1972

Language:

english

File:

PDF, 442 KB

english, 1972

16

Purification of human leukotriene C4 synthase from dimethylsulfoxide-differentiated U937 cells

Donald W. NICHOLSON, Michael W. KLEMBA, Dita M. RASPER, Kathleen M. METTERS, Robert J. ZAMBONI, Anthony W. FORD-HUTCHINSON

Journal:

Year:

1992

Language:

english

File:

PDF, 1.05 MB

english, 1992

17

Regulation of Leukotriene-Biosynthetic Enzymes During Differentiation of Myelocytic HL-60 Cells to Eosinophilic or Neutrophilic Cells

Kylie A. Scoggan, Donald W. Nicholson, Anthony W. Ford-Hutchinson

Journal:

Year:

1996

Language:

english

File:

PDF, 893 KB

english, 1996

18

Renal leukotriene C4 synthase: characterization, partial purification and alterations in experimental glomerulonephritis

Rosemary Petric, Donald W. Nicholson, Anthony W. Ford-Hutchinson

Journal:

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism

Year:

1995

Language:

english

File:

PDF, 926 KB

english, 1995

19

Leukotriene A5 is a substrate and an inhibitor of rat and human neutrophil LTA4 hydrolase

Dora J. Nathaniel, Jillian F. Evans, Yves Leblanc, Claire Léveillé, Brian J. Fitzsimmons, Anthony W. Ford-Hutchinson

Journal:

Biochemical and Biophysical Research Communications

Year:

1985

Language:

english

File:

PDF, 607 KB

english, 1985

20

The destruction of cytochrome P-450 by alclofenac: Possible involvement of an epoxide metabolite

Louise M. Brown, Anthony W. Ford-Hutchinson

Journal:

Biochemical Pharmacology

Year:

1982

Language:

english

File:

PDF, 617 KB

english, 1982

21

Potentiation of the inhibitory effect of a thromboxane A2 antagonist (L-640,035) on arterial thrombosis formation in rabbit by the angiotensin converting enzyme inhibitor enalapril

Chi-Chung Chan, Anthony Ford-Hutchinson

Journal:

European Journal of Pharmacology

Year:

1985

Language:

english

File:

PDF, 418 KB

english, 1985

22

The role of leukotriene D4 as a mediator of allergic conjunctivitis in the guinea-pig

Denis Garceau, Anthony W. Ford-Hutchinson

Journal:

European Journal of Pharmacology

Year:

1987

Language:

english

File:

PDF, 558 KB

english, 1987

23

Pharmacology of L-655,240 (3-[1-(4-chlorobenzyl)-5-fluoro-3-methyl-indol-2-yl]2,2-dimethylpropanoic acid); a potent, selective thromboxane/prostaglandin endoperoxide antagonist

Ronald A. Hall, John Gillard, Yvan Guindon, Gordon Letts, Eric Champion, Diane Ethier, Jillian Evans, Anthony W. Ford-Hutchinson, Réjean Fortin, Thomas R. Jones, Anne Lord, Howard E. Morton, Joshua Ro

Journal:

European Journal of Pharmacology

Year:

1987

Language:

english

File:

PDF, 667 KB

english, 1987

24

5-Lipoxygenase inhibitors and allergic conjunctivitis reactions in the guinea-pig

Denis Garceau, Anthony W. Ford-Hutchinson, Stella Charleson

Journal:

European Journal of Pharmacology

Year:

1987

Language:

english

File:

PDF, 564 KB

english, 1987

25

Eosinophil-eicosanoid interactions: inhibition of eosinophil chemotaxis in vivo by a LTD4-receptor antagonist

Chan Chi-Chung, Katherine McKee, Philip Tagari, Philip Chee, Anthony Ford-Hutchinson

Journal:

European Journal of Pharmacology

Year:

1990

Language:

english

File:

PDF, 953 KB

english, 1990

26

Characterization of the leukotriene D4 receptor in hyperreactive rat lung

Kathleen M. Metters, Elizabeth A. Frey, Anthony W. Ford-Hutchinson

Journal:

European Journal of Pharmacology

Year:

1991

Language:

english

File:

PDF, 1000 KB

english, 1991

27

Expression of mRNA for cyclooxygenase-1 and cyclooxygenase-2 in human tissues

Gary P. O'Neill, Anthony W. Ford-Hutchinson

Journal:

Year:

1993

Language:

english

File:

PDF, 663 KB

english, 1993

28

Photoaffinity labelling of human leukotriene C4 synthase in THP-1 cell membranes

Ambereen Ali, Robert J. Zamboni, Anthony W. Ford-Hutchinson, Donald W. Nicholson

Journal:

Year:

1993

Language:

english

File:

PDF, 786 KB

english, 1993

29

Inhibition of leukotriene biosynthesis improves renal function in experimental glomerulonephritis

Rosemary Petric, Anthony Ford-Hutchinson

Journal:

Journal of Lipid Mediators and Cell Signalling

Year:

1995

Language:

english

File:

PDF, 773 KB

english, 1995

30

Kinetic mechanism of glutathione conjugation to leukotriene A4 by leukotriene C4 synthase

Namrata Gupta, Michael J Gresser, Anthony W Ford-Hutchinson

Journal:

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism

Year:

1998

Language:

english

File:

PDF, 263 KB

english, 1998

31

Demonstration of cell-specific phosphorylation of LTC4 synthase

Namrata Gupta, Donald W. Nicholson, Anthony W. Ford-Hutchinson

Journal:

Year:

1999

Language:

english

File:

PDF, 161 KB

english, 1999

32

Characterization of microsomal GST-II by Western blot and identification of a novel LTC4 isomer

Per-Johan Jakobsson, Kylie A. Scoggan, James Yergey, Joseph A. Mancini, Anthony W. Ford-Hutchinson

Journal:

Journal of Lipid Mediators and Cell Signalling

Year:

1997

Language:

english

File:

PDF, 309 KB

english, 1997

33

A rapid biochemical method for measuring antigen-induced pulmonary eosinophil margination in allergic guinea pigs

Philip Tagari, Cheryl Black, Sean Marshall, Anthony W. Ford-Hutchinson

Journal:

Journal of Immunological Methods

Year:

1993

Language:

english

File:

PDF, 728 KB

english, 1993

34

Leukotriene B3, leukotriene B4 and leukotriene B5; Binding to leukotriene B4 receptors on rat and human leukocyte membranes

Stella Charleson, Jillian F. Evans, Robert J. Zamboni, Yves Leblanc, Brian J. Fitzsimmons, Claire Leveillé, Philippe Dupuis, Anthony W. Ford-Hutchinson

Journal:

Year:

1986

Language:

english

File:

PDF, 576 KB

english, 1986

35

FLAP: a novel drug target for inhibiting the synthesis of leukotrienes

Anthony W. Ford-Hutchinson

Journal:

Trends in Pharmacological Sciences

Year:

1991

Language:

english

File:

PDF, 373 KB

english, 1991

36

Membrane-associated Proteins in Eicosanoid and Glutathione Metabolism (MAPEG)

JAKOBSSON, PER-JOHAN, MORGENSTERN, RALF, MANCINI, JOSEPH, FORD-HUTCHINSON, ANTHONY, PERSSON, BENGT

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2000

Language:

english

File:

PDF, 105 KB

english, 2000

37

${}^{46}{\rm Scandium}$Metabolism; Binding to Metalloproteins in Vivo and in Vitro

Anthony W. Ford-Hutchinson and Deryck J. Perkins

Journal:

Radiation Research

Year:

1972

Language:

english

File:

PDF, 625 KB

english, 1972

38

Immediate hypersensitivity reactions in the guinea-pig conjunctiva: studies with a second-generation leukotriene D 4 receptor antagonist, MK-571

Chan, Chi-Chung, Dagenais, Francois, Firby, Patricia, Foster, Aidan, Ford-Hutchinson, Anthony W.

Journal:

Canadian Journal of Physiology and Pharmacology

Year:

1989

Language:

english

File:

PDF, 640 KB

english, 1989

39

5-Lipoxygenase Activation in Psoriasis: A Dead Issue?

Ford-Hutchinson, Anthony W.

Journal:

Skin Pharmacology and Applied Skin Physiology

Year:

1993

File:

PDF, 2.29 MB

1993

40

Urinary Leukotriene E 4 after Lysine-Aspirin Inhalation in Asthmatic Subjects

Christie, Pandora E., Tagari, Philip, Ford-Hutchinson, Anthony W., Black, Cheryl, Markendorf, Andre, Schmitz-Schumann, Michael, Lee, Tak H.

Journal:

American Review of Respiratory Disease

Year:

1992

Language:

english

File:

PDF, 387 KB

english, 1992

41

Urinary Leukotriene E 4 Concentrations Increase after Aspirin Challenge in Aspirin-sensitive Asthmatic Subjects

Christie, Pandora E., Tagari, Philip, Ford-Hutchinson, Anthony W., Charlesson, Stella, Chee, Philip, Arm, Jonathan P., Lee, Tak H.

Journal:

American Review of Respiratory Disease

Year:

1991

Language:

english

File:

PDF, 570 KB

english, 1991

42

Purification to Homogeneity and the N-Terminal Sequence of Human Leukotriene C4Synthase: A Homodimeric Glutathione S-Transferase Composed of 18-kDa Subunits

Donald W. Nicholson, Ambereen Ali, John P. Vaillancourt, Jimmy R. Calaycay, Richard A. Mumford, Robert J. Zamboni and Anthony W. Ford-Hutchinson

Journal:

Proceedings of the National Academy of Sciences

Year:

1993

Language:

english

File:

PDF, 1.07 MB

english, 1993

43

Levels of Peptidoleukotriene E4 Are Elevated in Active Crohnʼs Disease

Kim, Jae H., Tagari, Philip, Griffiths, Anne Marie, Ford-Hutchinson, Anthony, Smith, Claire, Sherman, Philip M.

Journal:

Journal of Pediatric Gastroenterology & Nutrition

Year:

1995

File:

PDF, 365 KB

1995

44

[Methods in Enzymology] Immunochemical Techniques Part M: Chemotaxis and Inflammation Volume 163 || [30] Leukotriene B4 receptors on rat and human neutrophil membranes

Ford-Hutchinson, Anthony W.

Year:

1988

Language:

english

File:

PDF, 202 KB

english, 1988

45

[Methods in Enzymology] Immunochemical Techniques Part L: Chemotaxis and Inflammation Volume 162 || [7] Neutrophil aggregation and chemokinesis assays

Ford-Hutchinson, Anthony W.

Year:

1988

Language:

english

File:

PDF, 1.07 MB

english, 1988

46

Activation of Human Eosinophils and Differentiated HL-60 Cells by lnterleukin-5

Tagari, Philip, Pecheur, Eve-Isabelle, Scheid, Michael, Brown, Pamela, Ford-Hutchinson, Anthony W., Nicholson, Donald

Journal:

International Archives of Allergy and Immunology

Year:

1993

Language:

english

File:

PDF, 1.14 MB

english, 1993